Ever heard of Hirschsprung disease?

by Cheungy55 on May 10, 2017 - 12:31am

Hirschsprung disease affects the large intestine of newborns, babies, and todadlers. It can cause constipation, diarrhea, and vomiting and sometimes lead to serious colon complications, like enterocolitis and toxic megacolon, which can be life-threatening. Children who have Hirschsprung disease are missing those nerves along part of the length of their colons.

Hirschsprung disease can affect the entire large intestine, which is called long-segment disease, or it can affect a shorter length of the colon closer to the rectum. Doctors aren't entirely sure why some children get Hirschsprung disease, but they do know it can run in families and affects boys more often than girls.

Newborns with Hirschsprung disease may show these signs: inability to pass stool within the first or second day of life swollen belly, bloating, or gas diarrhea vomiting, which may include vomiting a green or brown substance Inability to poop within the first 48 hours of life is often the key to detecting Hirschsprung disease in a newborn. To diagnose Hirschsprung disease, doctors often do a test called a barium enema which involves barium, a dye that is put into the colon using an enema. The barium shows up better on X-rays and can help doctors get a clearer picture of the colon.  Surgery is thought to be the most effective treatment for Hirschsprung disease.

I thought this would be pretty revelent knowing many babies are reproduced very year.


Arshad, A., Powell, C., & Tighe, M. (2012). EASILY MISSED?: Hirschsprung's disease. BMJ: British Medical Journal, 345(7883), 47-49. 


I have not, in fact, heard of Hirschsprung's disease until now! It is said to be more common on boys. Is it so much more common that it may be an X-lined disease?

I believe there are many other diseases have the same symptoms like this one. But is there a particular location/area provided? Is this involved with the environment or food sources? Or maybe a sex-linked disease?

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