The Ultimate Way of Curation is Close to Be Reality?

by Raphael Audet on September 18, 2017 - 8:13am

On September 1st of 2017, the science journalist John Horgan wrote an article for the “Cross-Check” blog on the Scientific American's website. This article is titled “Has the Era of Gene Therapy Finally Arrived?” 

As the title of this article suggests, the subject discuss is the gene therapy. This therapy consists of modifying specific genes in order to destroy diseases that have the ability to take human lives. Indeed, genetic research that is made on this is very important for the population because as well as having the ambition to eliminate diseases such as cancer, they also have the objective to be able to “engineered “designer babies” who would grow up to be smarter than Nobel laureates and more athletic than Olympians” (Horgan, par. 5). The article also gives a historical summary of the genetic research for the purpose of this therapy.

This subject found his way on the news because recently, Kymriah became the first gene therapy to be approved in the United States by the Food and Drug Administration (FDA). This revolutionary therapy is used to cure “a form of childhood leukemia” and was “produced by Navartis” (Horgan, par. 3). This news makes the dream of having an ultimate way to cure deadly diseases more possible than ever.

However, even though this recent event is a historical step in medical and genetic research, it can be a source of debate and this is where the article by John Horgan gets all its importance. Indeed, the author bring up all the reasons why the genetic therapy is not ready to be practised as of today and in a near future. Subjects such as the health risks, the cost and the ethical issue that are related to gene therapy are well-discussed in the text.

To resume, the impact of genetic therapy is undeniable on the population's health in undeniable. Thus, everyone must be well-informed about every single aspect that it implies and the best way to achieve this is to read the article, “Has the Era of Gene Therapy Finally Arrived?” that can be found on the website of the magazine Scientific American

 

Here is the link to read the article: https://blogs.scientificamerican.com/cross-check/has-the-era-of-gene-therapy-finally-arrived/

Comments

Hi Raphael,

From the beginning of your literature review, you have clearly presented the topic analyzed in the article, which is the gene therapy, while identifying the important elements related to it. In other words, the fact that you have given us a brief description of the subject, a glimpse of the paper’s content and some examples through your commentary emphasize our desire to read the article. You have also provided benchmarks for recent clinical trials that have advanced gene therapy. By designating the first gene therapy approved in an influential country, readers are more inclined to believe the relevance of the article’s content and that was indeed my case. Moreover, although you have mentioned the possible positive effects on the population, you have not neglected to mention the negative consequences that genetic therapy can generate on humans. Therefore, you succeed in captivating our attention on the advantages as well as the drawbacks, forcing us to read the full article to find out more. Finally, you have finished your commentary by introducing the result of these therapies without necessarily revealing the actual conclusion suggested in the article. I think it's a very good way to convince people to continue their reading.

I strongly suggest you to read “The Future of Gene Therapy”. As in your article, it refers to previous clinical trials, but it indicates more details that support conjectures on gene therapy. Only a few lines of your article are dedicated to the predictions of this treatment whereas in this one, several paragraphs discuss the perspective for gene therapy. It's very interesting to know what scientists forecast as a result of this therapy because the population outcome is inconsistent. Also, the article presents an additional essential element that is the constraints of this type of therapy. Genetic healing can be used with three different applications, but no matter the one used, obstacles will always prevent successful development. To enhance your knowledge of the complexity of genes treatment, it is important to be acquainted of the possible hurdles that are a real influencing factor of the therapy. Furthermore, the article provided the analysis of many statistics on the transfer protocols of human genes, which allows the readers to have a numerological interpretation of the information. The article also quotes the opinion of two experts helping the credibility of the content. Finally, a large amount of additional information about genes, such as the study of vectors used, that is not disclosed in your article is transmitted through this one. Therefore, to do advanced research on the subject, I advise you to visit the following site; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564347/