Get Rid of Your Brown Spots and Wrinkled Skin, No One Needs Them!
by ariane.r on November 6, 2013 - 8:40pm
Skin is the most interesting part of the human body. Why? There are so many external factors that can influence how your skin will develop and how it will get old. A major fear for women is to start seeing deep wrinkles and dark spots on their skin. The skin aging is something you can’t avoid, but you certainly can do something to at least slow the process.
A study from the University of Michigan shows that topical vitamin A, also called retinol, has a determinant effect on the signs of aging on the skin. In general, retinoid treatments will “reduce matrix metalloproteinase expression and stimulates collagen synthesis in natural aged, sun-protected skin, as it does in photoaged skin.” Because ultraviolet irradiation is really harmful for the skin, it creates “amorphous elastotic material” which when accumulated occurs in photoaging. The conclusion of the study shows that fibroblast proliferation has been reduced, matrix metalloproteinase increased, and finally the topical retinol “reduced elaboration of new collagen (mRNA and protein)”. In other words, the study shows evidences in a sense that “topical retinoid treatment may partially reverse the changes observed in the aged skin”.
Another article that I found on Science Daily’s website provides almost the same results as the study above. In summary, a study conducted by Reza Kafi, M.D, concludes that retinol-treated aged skin shows less “skin injuries and ulcer formation along with improved appearance.” The individuals participating in the study were applying vitamin A lotion for a period of 24 weeks. At the end, Kafi and his colleagues state: “wrinkles, roughness, and overall aging severity were all significantly reduced [by the vitamin A lotion]”. The author also said that sun exposed skin is more likely to have deep wrinkles and brown spot dramatically and younger.
These two articles are showing almost the same results except that they used different ways to evaluate the thesis. The academic journal presents an experience on individuals where the retinol was “applied under occlusion to prevent drug loss”. On the other hand, the study leads by Reza Kafi used the retinol under the form of a lotion, which could be less efficient for concrete results. In sense of sources, the two are reliable ones and the authors came from the same university, which is the University of Michigan. The studies were not made at the same time, the first one happened in 2000 and the other one was concluded in 2007. Thus, this shows us that they both have similar results even if in 2000, we didn’t have the same technology as in 2007. I finally want to point out that I will recommended the academic journal (the first article) if I had to choose between the two because it is much longer and it is well explained if you understand the biologic terms. In conclusion, both studies clearly affirmed that vitamin A is a good treatment for skin aging even if your skin is photoaged because of UV radiation.